Shanghai Pemichem Lab Supply Raw Materials Pharmaceutical Intermediates Powder Pimodivir CAS 1629869-44-8 API with 99% Pruity

• Customization: Available
• CAS No.: 1629869-44-8
• Formula: C20h19f2n5o2
• Model NO.: Pemi-0665
• EINECS: -
• Classification: Organic Analytical Reagents
• Grade: GR
• Content: Standard
• Usage: Laboratory Reagents
• Source: Concrete
• Habit Appellation: Fine Chemicals
• Application: Scientific Research
• Property: Organic Reagent
• MW: 399.39
• Transport Package: Penicillin Bottle, Aluminium Foil Bag
• Specification: 1g, 100g
• Origin: Shanghai
• Production Capacity: 5000kg/Year

Product Description

1.For some materials, we could supply free Samples for testing at first..
2.MOQ: 1g or 5g
3.More than 3000 kinds of materials in stock.
4.More than 11+ manufacturing experience.
5.Certification: MSDS,HALAL,COA,IFRA,ISO9001, ISO22000,26 Allergens, etc.
6.Lead time:about 8-12 working days.
8.Verified by Made-in-China as Golden Supplier.
9.We will reply you for your inquiry in 24 hours.
10. Our Q&C team will inspect every product quality strictly before delivery.

What is CAS 1629869-44-8 Pimodivir Powder? 
 

Product Name:	Pimodivir
Synonyms:	Pimodivir;Pimodivir (VX-787);VX-787;(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid;CS-2483;VRT 0928787;VRT0928787;VRT-0928787
CAS:	1629869-44-8
MF:	C20H19F2N5O2
MW:	399.39
EINECS:
Product Categories:
Mol File:	1629869-44-8.mol

     

Pimodivir is an inhibitor of influenza virus polymerase basic protein 2 (PB2; K_D = <0.003 μM). It also binds to glycogen synthase kinase 3β (GSK3β; K_i = ^~1.6 μM) and inhibits the activity of Axl and calcium/calmodulin-dependent protein kinase IIβ (CaMKIIβ) by greater than 50% in a panel of 65 human and rat kinases. Pimodivir decreases the replication of seven adamantine- and neuraminidase inhibitor-resistant strains of influenza virus A (EC₅₀s = <0.15-2.8 nM in a cell-based assay). It increases the antiviral activity of oseltam ivir , zanamivir , and favipiravir (T-705; ) with 50% combination index (CI₅₀) values of 0.58, 0.64, and 0.89, respectively, in a cell-based assay. Pimodivir increases survival in a mouse model of intranasal influenza A infection when administered at doses of 1, 3, and 10 mg/kg twice per day.
Pimodivir is an orally bioavailable azaindole inhibitor of influenza PB2.

 

 

 

 

 

 

 

 

 

 

ShangHai Pemichem is one of professional company specialized in research, development, custom manufacturing and trading of pharmaceutical API, advanced intermediates, Cosmetic raw materials, health and new raw materials, polypeptides, animal drug and organic reagent  etc. 
You can select more than 2000 kinds of raw ingredients here. And we are keeping developing new products and continuously marketing them for sale. You will save lots of time , energy, money and have a very pleasant cooperation with us!
Our purpose: Trransaction is not the end, but the satarting of service!


 

Q&A

1.How could l get a sample?
Before we received the first order, please afford the sample cost and express fee. We will return the sample cost back to you within your first order.

2.Can you make designs for us?
We have a professional design team to help our customers do design work.Both OEM and ODM    orders are accepted.


3.Whether you could make our brand on your products?
Yes. We can print your Logo on both the products and the packages if you can meet our MOQ.

4.How can you provide us high quality products?
We have a professional QC team, every product is shipped after strictly examination.

5.What is your lead time?
7-15days, We will update you eact two-three days!

6.What is your payment?
We accept T/T.L/C.Paypal.Westem union or to be negotiated.Don't worry about anything, if you have      any problems, please feel free to contact us