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What is CAS 119478-56-7 Merop enem Trihydrate Powder?
Product Name: |
Mero penem Trihydrate |
Synonyms: |
Merop enem;MERO PENEMTRIHYDRATE(3-[[5-[(DIMETHYLAMINO)CARBONYL]-3-PYRROLIDINYL]THIO]-6-(1-HYDROXYETHYL)-4-METHYL-7-OXO-1-AZABICYCLO[3,2,0]HEPT-2-ENE-2-CARBOXYLICACIDTRIHYDRATE);MERO PENEM WITH SODIUM CARBONATE;3-(5-Dimethylcarbamoyl-pyrrolidin-3-ylsulfanyl)-6-(1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicy;Mero penem (300 mg);(1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate;(4R,5S,6S)-3-{[(3S,5S)-5-(diMethylcarbaMoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-Methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;(4R,5S,6S)-3-[[(3S,5S)-5-[(DiMeth-ylaMino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-Methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate |
CAS: |
119478-56-7 |
MF: |
C17H27N3O6S |
MW: |
401.48 |
EINECS: |
1312995-182-4 |
Product Categories: |
API;119478-56-7 |
Mol File: |
119478-56-7.mol |
1. Mero penem trihydrate is a carbapenem antibiotic with wide spectrum of antibacterial. It is an ultra-broad spectrum beta-lactam antibiotic and has antibacterial activity against Gram-negative and Gram-positive bacteria as well as anaerobic microorganisms such as Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter species, Serratia marcescens, Streptococcus pyogenes, Streptococcus agalactiae and Citrobacter sp. Mero penem trihydrate is indicated for the treatment of serious bacterial infection including complicated skin infections, complicated intra-abdominal infections, urinary tract infections, severe pneumonia, broncho-pulmonary infections and bacterial meningitis.
2. Mero penem trihydrate is a thienamycin derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIP ENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of bacterial infections, including infections in immunocompromised patients.
Mero penem trihydrate has also been used in the
antibiotic susceptibility testing of E coli isolates from harbor estuary sediment samples.
in the bacterial killing assay and for screening antibiotic resistance of cystic fibrosis patient′s sputum based Staphylococcus aureus transformed macrophages in phagocyte infection.
for screening Enterococcus faecalis from human bile.
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