Shanghai Pemichem Supply Factory Price Pharmaceutical Powder 99% Purity for Weight Loss Powder CAS 7150-23-4 Raw Powder Stock Supply Jbsnf-000088

• Customization: Available
• CAS No.: 7150-23-4
• Formula: C7h8n2o2
• Model NO.: Pemi-0868
• EINECS: 604-604-1
• Classification: Organic Analytical Reagents
• Grade: GR
• Content: Standard
• Usage: Laboratory Reagents
• Source: Concrete
• Habit Appellation: Fine Chemicals
• Application: Scientific Research
• Property: Organic Reagent
• MW: 152.15
• Transport Package: Penicillin Bottle, Aluminium Foil Bag
• Specification: 1g, 100g
• Origin: Shanghai
• Production Capacity: 500kg/Year

Product Description

1.For some materials, we could supply free Samples for testing at first..
2.MOQ: 1g or 5g
3.More than 3000 kinds of materials in stock.
4.More than 11+ manufacturing experience.
5.Certification: MSDS,HALAL,COA,IFRA,ISO9001, ISO22000,26 Allergens, etc.
6.Lead time:about 8-12 working days.
8.Verified by Made-in-China as Golden Supplier.
9.We will reply you for your inquiry in 24 hours.
10. Our Q&C team will inspect every product quality strictly before delivery.

What is CAS 7150-23-4 6-Methoxynicotinamide Powder? 
 

 

Product Name:	6-Methoxynicotinamide
CAS:	7150-23-4
MF:	C7H8N2O2
MW:	152.15
EINECS:	604-604-1
Product Categories:

JBSNF-000088 is a cell penetrant, potent and selective inhibitor of Nicotinamide N-methyltransferase (NNMT) that reduces 1-methyl-nicotinamide (MNA) and improved glucose control in mice models of metabolic disease. JBSNF-000088 potently inhibits growth of PFA ependymoma cells.

 

JBSNF-000088 is an inhibitor of nicotinamide N-methyltransferase (NNMT; IC50s = 1.8, 2.8, and 5 µM for human, monkey, and mouse NNMT, respectively).1 It inhibits NNMT and reduces 1-methyl-nicotinamide (MNA) levels in U2OS and 3T3L1 cells (IC50s = 1.6 and 6.3 µM, respectively).

JBSNF-000088 (50 mg/kg) reduces visceral white adipose tissue (WAT) MNA levels, body weight, fed blood glucose levels, and plasma and liver triglyceride levels, and improves oral glucose tolerance in a mouse model of diet-induced obesity (DIO).

It also improves glucose tolerance, without affecting body weight, in the ob/ob and db/db mouse models of in sulin resistance and diabetes, respectivel

Each of these peptides has a positive impact of energy metabolism. NMN, for instance, boosts NAD levels. Low NAD has long been associated with obesity while high NAD is generally associated with healthy diets rich in vegetables. High levels of NAD are associated with ideal body mass composition and increased longevity. High NAD levels will definitely increase energy metabolism and lower obesity.

All three of these compounds can help to reduce the risk of diabetes. JBSNF-000088 is the most potent anti-diabetic in this group and has been shown in mouse models to drastically improve glucose handling, even in genetically obese mice.

Like JBSNF-000088, 5 amino-1MQ helps to regulate blood sugar levels by decreasing activity of NNMT. In this case, the research indicates that 5-amino-1MQ increases the transport of glucose by boosting GLUT-4 expression.

NAD is a primary marker of aging, declining over time and in certain disease conditions. NMN enhances NAD biosynthesis. In mouse models, NMN administration has been shown to mitigate age-related physiological decline without any side effects.

 

 

 

 

 

 

 

 

ShangHai Pemichem is one of professional company specialized in research, development, custom manufacturing and trading of pharmaceutical API, advanced intermediates, Cosmetic raw materials, health and new raw materials, polypeptides, animal drug and organic reagent  etc. 
You can select more than 2000 kinds of raw ingredients here. And we are keeping developing new products and continuously marketing them for sale. You will save lots of time , energy, money and have a very pleasant cooperation with us!
Our purpose: Trransaction is not the end, but the satarting of service!


 

Q&A

1.How could l get a sample?
Before we received the first order, please afford the sample cost and express fee. We will return the sample cost back to you within your first order.

2.Can you make designs for us?
We have a professional design team to help our customers do design work.Both OEM and ODM orders are accepted.


3.Whether you could make our brand on your products?
Yes. We can print your Logo on both the products and the packages if you can meet our MOQ.

4.How can you provide us high quality products?
We have a professional QC team, every product is shipped after strictly examination.

5.What is your lead time?
7-15days, We will update you eact two-three days!

6.What is your payment?
We accept T/T.L/C.Paypal.Westem union or to be negotiated.Don't worry about anything, if you have any problems, please feel free to contact us.