1.For some materials, we could supply free Samples for testing at first..
2.MOQ: 1g or 5g
3.More than 3000 kinds of materials in stock.
4.More than 11+ manufacturing experience.
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10. Our Q&C team will inspect every product quality strictly before delivery.
What is CAS 497223-25-3 Cenicriviroc(TAK-652) Powder?
Product Name: |
Cenicriviroc |
Synonyms: |
Cenicriviroc;TAK652;Cenicriviroc mesylate (TAK-652);Cenicriviroc(TAK652);TAK-652; TAK652; TAK 652; TBR-652; TBR 652; TBR652; CENICRIVIROC.;CS-2572;TAK-652; TBR-652; TAK652; TBR652; TAK 652; TBR 652;TBR 652 |
CAS: |
497223-25-3 |
MF: |
C41H52N4O4S |
MW: |
696.94 |
EINECS: |
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Product Categories: |
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Mol File: |
497223-25-3.mol |
1.Cenicriviroc is a dual antagonist of chemokine receptor types 2 and 5 (CCR2/CCR5). The receptors are found on Kupffer cells and hepatic stellate cells, and preclinical studies suggest its anti-inflammatory and anti-fibrotic activity. In the phase 2b CENTAUR study, cenicriviroc treatment for 1 year failed to achieve the primary outcome of a decrease in NAFLD activity score by ≥2 points with no worsening of fibrosis. Nonetheless, one of the key secondary outcomes, improvement in liver fibrosis without worsening of NASH, was achieved in 20% in the treatment group, compared with 10% in the placebo group. Besides, cenicriviroc reduced the serum levels interleukin- 6, C-reactive protein and fibrinogen, suggesting its action on inflammation that may not be reflected by crude histological assessment. A phase 3 study is planned.
2. Cenicriviroc is an experimental drug candidate for the treatment of HIV infection. It is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell.
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Q&A
1.How could l get a sample?
Before we received the first order, please afford the sample cost and express fee. We will return the sample cost back to you within your first order.
2.Can you make designs for us?
We have a professional design team to help our customers do design work.Both OEM and ODM orders are accepted.
3.Whether you could make our brand on your products?
Yes. We can print your Logo on both the products and the packages if you can meet our MOQ.
4.How can you provide us high quality products?
We have a professional QC team, every product is shipped after strictly examination.
5.What is your lead time?
7-15days, We will update you eact two-three days!
6.What is your payment?
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